Improved effect of a mitochondria-targeted antioxidant on hydrogen peroxide-induced oxidative stress in human retinal pigment epithelium cells

Abstract Background Oxidative damage to retinal pigment epithelial (RPE) cells contributes to the development of age-related macular degeneration, which is among the leading causes of visual loss in elderly people. In the present study, we evaluated the protective role of triphenylphosphonium (TPP)-...

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Bibliographic Details
Main Authors: Myung Hee Kim, Do-Hun Kim, Su Geun Yang, Dae Yu Kim
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Pharmacology and Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s40360-020-00471-w