Effects of synthetic silymarin-PLGA nanoparticles on M2 polarization and inflammatory cytokines in LPS-treated murine peritoneal macrophages

Effects of synthetic silymarin-PLGA nanoparticles on M2 polarization and inflammatory cytokines in LPS-treated murine peritoneal macrophages

Objective(s): Silymarin (SM) is a natural antioxidant compound with good anti-inflammatory effects, but its poor water solubility restricts its usage. Today, nanomaterial compounds (such as PLGA Poly D, L-lactic-co-glycolic acid) can provide a proper drug delivery system and help improve the accessi...

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Bibliographic Details
Main Authors: Mojgan Azadpour, Mohammad Morad Farajollahi, Hassan Dariushnejad, Ali Mohammad Varzi, Amir Varezardi, Mitra Barati
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2021-10-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
cytokines
nanoparticles
plga compound
peritoneal macrophages
silymarin
Online Access:https://ijbms.mums.ac.ir/article_18758_5474a061ba97022bfe0b46420fbd8902.pdf

Internet

https://ijbms.mums.ac.ir/article_18758_5474a061ba97022bfe0b46420fbd8902.pdf

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