Knockdown of KLF5 ameliorates renal fibrosis in MRL/lpr mice via inhibition of MX1 transcription

Abstract Objective This study aims to elucidate the role of Kruppel‐like factor (KLF5) and myxovirus resistance 1 (MX1) in the progression of renal fibrosis in lupus nephritis (LN). Methods First, the expression of KLF5 and MX1 was assessed in the peripheral blood of LN patients and healthy particip...

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Bibliographic Details
Main Authors: Shanshan Tao, Xiao Tan, Wen Chai, Xiaojie Peng, Weimin Zheng, Rui Fu, Meihui Deng
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Immunity, Inflammation and Disease
Subjects:
Online Access:https://doi.org/10.1002/iid3.937