The small RNA mascRNA differentially regulates TLR-induced proinflammatory and antiviral responses

MALAT1-associated small cytoplasmic RNA (mascRNA) is a highly conserved transfer RNA–like (tRNA-like) noncoding RNA whose function remains largely unknown. We show here that this small RNA molecule played a role in the stringent control of TLR-mediated innate immune responses. mascRNA inhibited acti...

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Bibliographic Details
Main Authors: Tao Sun, Chunxue Wei, Daoyong Wang, Xuxu Wang, Jiao Wang, Yuqing Hu, Xiaohua Mao
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-11-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.150833