Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain

Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain

A new sample preparation method coupled to GC-MS analysis was developed and validated for quantification of sulfate esters of pregnenolone (PREG-S) and dehydroepiandrosterone (DHEA-S) in rat brain. Using a solid-phase extraction recycling protocol, the results show that little or no PREG-S and DHEA-...

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Bibliographic Details
Main Authors: Philippe Liere, Antoine Pianos, Bernard Eychenne, Annie Cambourg, Suya Liu, William Griffiths, Michael Schumacher, Jan Sjövall, Etienne-Emile Baulieu
Format: Article
Language:English
Published: Elsevier 2004-12-01
Series:Journal of Lipid Research
Subjects:
pregnenolone sulfate
dehydroepiandrosterone sulfate
solid-phase extraction
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520341092

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http://www.sciencedirect.com/science/article/pii/S0022227520341092

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