Efficacy of short-course colchicine treatment in hospitalized patients with moderate to severe COVID-19 pneumonia and hyperinflammation: a randomized clinical trial

Abstract Some patients with COVID-19 pneumonia develop an associated cytokine storm syndrome that aggravates the pulmonary disease. These patients may benefit of anti-inflammatory treatment. The role of colchicine in hospitalized patients with COVID-19 pneumonia and established hyperinflammation rem...

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Main Authors: Alberto Cecconi, Pablo Martinez-Vives, Alberto Vera, Cristina Lavilla Olleros, Ana Barrios, Eva Fonseca Aizpuru, Pilar Roquero, Susana Hernandez Muñiz, Maria Jose Olivera, Marianela Ciudad, Ruben Pampin Sanchez, Rosa Fernandez-Madera Martínez, Azucena Bautista-Hernández, Elena García Castillo, Gorane Iturricastillo, Elena Ávalos, Diana Prada Cotado, Alvaro Alejandre de Oña, Eduardo Fernandez Carracedo, Ana Marcos-Jimenez, Ancor Sanz-Garcia, Aranzazu Alfranca, Maurizio Cecconi, Hortensia de La Fuente, Maria Angeles Sanz de Benito, Paloma Caballero, Francisco Sanchez-Madrid, Julio Ancochea, Carmen Suarez, Luis Jesus Jimenez-Borreguero, Fernando Alfonso
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13424-6