Network pharmacology and experimental validation to study the potential mechanism of Tongguanteng injection in regulating apoptosis in osteosarcoma

Network pharmacology and experimental validation to study the potential mechanism of Tongguanteng injection in regulating apoptosis in osteosarcoma

Abstract Objective The main objectives of this study were to identify the active components of Tongguanteng injection (TGT) and investigate the preclinical efficacy and mechanism of TGT on osteosarcoma using a combination of network pharmacology and experimental validation. Methods To identify the a...

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Bibliographic Details
Main Authors: Lanyi Wei, Jingjing Meng, Danfeng Xiang, Quanjun Yang, Yangyun Zhou, Lingyan Xu, Mengyue Wang, Junjun Chen, Yonglong Han
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Tongguanteng injection
Osteosarcoma
Apoptosis
Network pharmacology
Molecular docking
Online Access:https://doi.org/10.1186/s12906-024-04354-z

Internet

https://doi.org/10.1186/s12906-024-04354-z

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