The Role of α3β1 Integrin Modulation on Fabry Disease Podocyte Injury and Kidney Impairment

The Role of α3β1 Integrin Modulation on Fabry Disease Podocyte Injury and Kidney Impairment

Podocyte dysfunction plays a crucial role in renal injury and is identified as a key contributor to proteinuria in Fabry disease (FD), primarily impacting glomerular filtration function (GFF). The α3β1 integrins are important for podocyte adhesion to the glomerular basement membrane, and disturbance...

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Bibliographic Details
Main Authors: Bruna Bosquetti, Aline Aparecida Santana, Paulo Cézar Gregório, Regiane Stafim da Cunha, Guilherme Miniskiskosky, Julia Budag, Célia Regina Cavichiolo Franco, Edneia Amancio de Souza Ramos, Fellype Carvalho Barreto, Andréa Emilia Marques Stinghen
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Toxins
Subjects:
chloroquine
Fabry disease
podocyte injury
Online Access:https://www.mdpi.com/2072-6651/15/12/700

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https://www.mdpi.com/2072-6651/15/12/700

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