Potential Prognostic Value of GATA4 Depends on the p53 Expression in Primary Glioblastoma Patients

Potential Prognostic Value of GATA4 Depends on the p53 Expression in Primary Glioblastoma Patients

Background: Primary glioblastoma is characterized by an extremely poor prognosis. The promoter methylation of <i>GATA4</i> leads to the loss of its expression in many cancer types. The formation of high-grade astrocytomas can be promoted by the concurrent loss of <i>TP53</i>...

Full description

Bibliographic Details
Main Authors: Berenika Trąbska-Kluch, Marcin Braun, Magdalena Orzechowska, Sylwia Paszek, Alina Zuchowska, Julia Sołek, Adam Kluska, Jacek Fijuth, Dorota Jesionek-Kupnicka, Izabela Zawlik
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Genes
Subjects:
glioblastoma
<i>GATA4</i> promoter methylation
GATA4 protein expression
TP53 abnormalities
Online Access:https://www.mdpi.com/2073-4425/14/6/1146

Internet

https://www.mdpi.com/2073-4425/14/6/1146

Similar Items