FXR, a Key Regulator of Lipid Metabolism, Is Inhibited by ER Stress-Mediated Activation of JNK and p38 MAPK in Large Yellow Croakers (<i>Larimichthys crocea</i>) Fed High Fat Diets

FXR, a Key Regulator of Lipid Metabolism, Is Inhibited by ER Stress-Mediated Activation of JNK and p38 MAPK in Large Yellow Croakers (<i>Larimichthys crocea</i>) Fed High Fat Diets

High-fat diets induced abnormal lipid accumulation in the liver of cultured fish that caused body damage and diseases. The purpose of this research was to investigate the role and mechanism of farnesoid X receptor (FXR) in regulating lipid metabolism and to determine how high-fat diets affect FXR ex...

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Bibliographic Details
Main Authors: Jianlong Du, Xiaojun Xiang, Dan Xu, Junzhi Zhang, Wei Fang, Wei Xu, Kangsen Mai, Qinghui Ai
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Nutrients
Subjects:
high-fat diets
FXR
lipid metabolism
ER stress
MAPK
Online Access:https://www.mdpi.com/2072-6643/13/12/4343

Internet

https://www.mdpi.com/2072-6643/13/12/4343

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