Chaihu Shugan powder restores fatty acid synthesis to alleviate insulin resistance in metabolic syndrome by regulating the LXRα/SREBP-1 signaling pathway

Chaihu Shugan powder restores fatty acid synthesis to alleviate insulin resistance in metabolic syndrome by regulating the LXRα/SREBP-1 signaling pathway

BackgroundMetabolic syndrome (MS) is a significant risk factor for cardiovascular and cerebrovascular diseases, primarily driven by insulin resistance (IR). Although the herbal compound Chaihu Shugan powder (CSP) has demonstrated the potential to improve IR in animal models of MS, its mechanism of a...

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Bibliographic Details
Main Authors: Sisi Lei, Weihang Peng, Lulu Wu, Liyuan Yu, Meida Wang, Qingmin Li, Yi Deng, Shuai Zhao, Peiying Huang, Bojun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
Subjects:
Chaihu Shugan powder
metabolic syndrome
insulin resistance
LXRα/SREBP-1
fatty acid synthesis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1442279/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1442279/full

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