MUC13 Cell Surface Mucin Limits Salmonella Typhimurium Infection by Protecting the Mucosal Epithelial BarrierSummary

MUC13 Cell Surface Mucin Limits Salmonella Typhimurium Infection by Protecting the Mucosal Epithelial BarrierSummary

Background & Aims: MUC13 cell surface mucin is highly expressed on the mucosal surface throughout the intestine, yet its role against bacterial infection is unknown. We investigated how MUC13 impacts Salmonella typhimurium (S Tm) infection and elucidated its mechanisms of action. Methods: Mu...

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Bibliographic Details
Main Authors: Michael A. McGuckin, Julie M. Davies, Pascal Felgner, Kuan Yau Wong, Rabina Giri, Yaowu He, Md Moniruzzaman, Thomas Kryza, Haressh Sajiir, John D. Hooper, Timothy H. Florin, Jakob Begun, Abderrahim Oussalah, Sumaira Z. Hasnain, Michael Hensel, Yong H. Sheng
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Salmonella
Bacterial Invasion
Intestinal Barrier
Epithelial Cell
Mucin
MUC13
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X23001595

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http://www.sciencedirect.com/science/article/pii/S2352345X23001595

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