Rutin mitigates hepatic fibrogenesis and inflammation through targeting TLR4 and P2X7 receptor signaling pathway in vitro and in vivo

Rutin mitigates hepatic fibrogenesis and inflammation through targeting TLR4 and P2X7 receptor signaling pathway in vitro and in vivo

Rutin is a flavonol glycoside widely existing in plants, used as food antioxidant and nutritional enhancer. Rutin has vitamin P-like effect and anti-inflammatory effect. This study aims to investigate the effects and potential mechanisms of rutin against hepatic fibrosis in vivo and in vitro. The pr...

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Bibliographic Details
Main Authors: Li-Shuang Hou, Zhen-Yu Cui, Peng Sun, Hui-Qing Piao, Xin Han, Jian Song, Ge Wang, Shuang Zheng, Xiu-Xiu Dong, Lu Gao, Yue Zhu, Li-Hua Lian, Ji-Xing Nan, Yan-Ling Wu
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of Functional Foods
Subjects:
Rutin
Hepatic fibrosis
Inflammation
TLRs
P2X7r
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464619306243

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http://www.sciencedirect.com/science/article/pii/S1756464619306243

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