SARS-CoV-2 leads to a small vessel endotheliitis in the heart

SARS-CoV-2 leads to a small vessel endotheliitis in the heart

Background: SARS-CoV-2 infection (COVID-19 disease) can induce systemic vascular involvement contributing to morbidity and mortality. SARS-CoV-2 targets epithelial and endothelial cells through the ACE2 receptor. The anatomical involvement of the coronary tree is not explored yet. Methods: Cardiac a...

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Bibliographic Details
Main Authors: Umberto Maccio, Annelies S. Zinkernagel, Srikanth Mairpady Shambat, Xiankun Zeng, Gieri Cathomas, Frank Ruschitzka, Reto A. Schuepbach, Holger Moch, Zsuzsanna Varga
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:EBioMedicine
Subjects:
COVID-19
Endothelial dysfunction
Epicardial capillaries
Epicardial nerves
Coronary arteries
ACE2-receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420305582

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http://www.sciencedirect.com/science/article/pii/S2352396420305582

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