The interplay of poorly soluble drugs in dissolution from amorphous solid dispersions

In recent years, the application of fixed dose combinations of antiretroviral drugs in HIV therapy has been established. Despite numerous therapeutic benefits, this approach poses several challenges for the formulation development especially when poorly soluble drugs are considered. Amorphous solid...

Full description

Bibliographic Details
Main Authors: Marcel Kokott, Jörg Breitkreutz, Raphael Wiedey
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:International Journal of Pharmaceutics: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S259015672400015X