Mechanisms and treatment strategies of demyelinating and dysmyelinating Charcot-Marie-Tooth disease

Mechanisms and treatment strategies of demyelinating and dysmyelinating Charcot-Marie-Tooth disease

Schwann cells, the myelinating glia of the peripheral nervous system, wrap axons multiple times to build their myelin sheath. Myelin is of paramount importance for axonal integrity and fast axon potential propagation. However, myelin is lacking or dysfunctional in several neuropathies including demy...

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Bibliographic Details
Main Authors: Nadège Hertzog, Claire Jacob
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
charcot-marie-tooth disease; rodent models; emerging treatments; demyelination and dysmyelination; endoplasmic reticulum stress; gene therapy; myelin; repair; schwann cells; unfolded protein response
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=9;spage=1931;epage=1939;aulast=Hertzog

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=9;spage=1931;epage=1939;aulast=Hertzog

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