Oxidative Inactivation of the Proteasome Augments Alveolar Macrophage Secretion of Vesicular SOCS3

Extracellular vesicles (EVs) contain a diverse array of molecular cargoes that alter cellular phenotype and function following internalization by recipient cells. In the lung, alveolar macrophages (AMs) secrete EVs containing suppressor of cytokine signaling 3 (SOCS3), a cytosolic protein that promo...

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Bibliographic Details
Main Authors: Mikel D. Haggadone, Peter Mancuso, Marc Peters-Golden
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/7/1589