Lyophilized apoptotic vesicle-encapsulated adhesive hydrogel sponge as a rapid hemostat for traumatic hemorrhage in coagulopathy

Lyophilized apoptotic vesicle-encapsulated adhesive hydrogel sponge as a rapid hemostat for traumatic hemorrhage in coagulopathy

Abstract Rapid hemostasis of uncontrolled bleeding following traumatic injuries, especially accompanied by coagulopathies, remains a significant clinical challenge. Extracellular vesicles (EVs) show therapeutic effects for fast clotting. However, low yield, specific storage conditions, and lack of p...

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Bibliographic Details
Main Authors: Yexiang Jiang, Meng Hao, Fenglin Jiang, Jiwu Li, Kunkun Yang, Can Li, Lan Ma, Shiyu Liu, Xiaoxing Kou, Songtao Shi, Xin Ding, Xiao Zhang, Jianxia Tang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Nanobiotechnology
Subjects:
Apoptotic vesicles
Exosomes
Hemostasis
Hydrogel sponge
Lyophilization
Hemorrhage
Online Access:https://doi.org/10.1186/s12951-023-02128-2

Internet

https://doi.org/10.1186/s12951-023-02128-2

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