Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A

Vpr is a HIV-1 accessory virulence factor that also interacts with the human DNA repair protein hHR23A. Here, the authors present the structure of Vpr in complex with the C-terminal half of hHR23A comprising the XPC-binding and ubiquitin-associated domains, which reveals that hHR23A interacts with t...

Full description

Bibliographic Details
Main Authors: In-Ja L. Byeon, Guillermo Calero, Ying Wu, Chang H. Byeon, Jinwon Jung, Maria DeLucia, Xiaohong Zhou, Simon Weiss, Jinwoo Ahn, Caili Hao, Jacek Skowronski, Angela M. Gronenborn
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-27009-w