CD209/CD14+ Dendritic Cells Characterization in Rheumatoid and Psoriatic Arthritis Patients: Activation, Synovial Infiltration, and Therapeutic Targeting

CD209/CD14+ Dendritic Cells Characterization in Rheumatoid and Psoriatic Arthritis Patients: Activation, Synovial Infiltration, and Therapeutic Targeting

Dendritic cells (DC) have a key role in the initiation and progression of inflammatory arthritis (IA). In this study, we identified a DC population that derive from monocytes, characterized as CD209/CD14+ DC, expressing classical DC markers (HLADR, CD11c) and the Mo-DC marker (CD209), while also ret...

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Bibliographic Details
Main Authors: Viviana Marzaioli, Mary Canavan, Achilleas Floudas, Keelin Flynn, Ronan Mullan, Douglas J. Veale, Ursula Fearon
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
monocyte-derived dendritic cells (MoDC)
rheumatoid arthritis
psoriatic arthritis
cell development
inflammation
JAK - STAT signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.722349/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.722349/full

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