Screening for Small Molecule Modulators of <i>Trypanosoma brucei</i> Hsp70 Chaperone Activity Based upon Alcyonarian Coral-Derived Natural Products
The <i>Trypanosoma brucei</i> Hsp70/J-protein machinery plays an essential role in survival, differentiation, and pathogenesis of the protozoan parasite, and is an emerging target against African Trypanosomiasis. This study evaluated a set of small molecules, inspired by the malonganenon...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-01-01
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Series: | Marine Drugs |
Subjects: | |
Online Access: | https://www.mdpi.com/1660-3397/18/2/81 |