3D-Printed Tumor-on-a-Chip Model for Investigating the Effect of Matrix Stiffness on Glioblastoma Tumor Invasion

Glioblastoma multiform (GBM) tumor progression has been recognized to be correlated with extracellular matrix (ECM) stiffness. Dynamic variation of tumor ECM is primarily regulated by a family of enzymes which induce remodeling and degradation. In this paper, we investigated the effect of matrix sti...

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Bibliographic Details
Main Authors: Meitham Amereh, Amir Seyfoori, Briana Dallinger, Mostafa Azimzadeh, Evan Stefanek, Mohsen Akbari
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomimetics
Subjects:
Online Access:https://www.mdpi.com/2313-7673/8/5/421