Next‐generation sequencing‐based analysis to assess the pattern of relapse in patients with Philadelphia‐positive acute lymphoblastic leukemia
Abstract In this study, we performed serial monitoring using targeted DNA sequencing to identify genetic alterations in adults with Philadelphia‐positive acute lymphoblastic leukemia (Ph‐ALL). Deep sequencing was performed by targeting the coding regions of 45 genes with recurrent driver mutations a...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-11-01
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Series: | eJHaem |
Subjects: | |
Online Access: | https://doi.org/10.1002/jha2.514 |