Adhatoda Vasica attenuates inflammatory and hypoxic responses in preclinical mouse models: potential for repurposing in COVID-19-like conditions

Adhatoda Vasica attenuates inflammatory and hypoxic responses in preclinical mouse models: potential for repurposing in COVID-19-like conditions

Abstract Background COVID-19 pneumonia has been associated with severe acute hypoxia, sepsis-like states, thrombosis and chronic sequelae including persisting hypoxia and fibrosis. The molecular hypoxia response pathway has been associated with such pathologies and our recent observations on anti-hy...

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Bibliographic Details
Main Authors: Atish Gheware, Dhwani Dholakia, Sadasivam Kannan, Lipsa Panda, Ritu Rani, Bijay Ranjan Pattnaik, Vaibhav Jain, Yash Parekh, M. Ghalib Enayathullah, Kiran Kumar Bokara, Venkatesan Subramanian, Mitali Mukerji, Anurag Agrawal, Bhavana Prasher
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Respiratory Research
Subjects:
Hypoxia
Fibrosis
Sepsis
Angiogenesis
Blood coagulation
SARS-CoV2
Online Access:https://doi.org/10.1186/s12931-021-01698-9

Internet

https://doi.org/10.1186/s12931-021-01698-9

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