The BRCAness Landscape of Cancer
BRCAness refers to the damaged homologous recombination (HR) function due to the defects in HR-involved non-<i>BRCA1/2</i> genes. BRCAness is the important marker for the use of synthetic lethal-based PARP inhibitor therapy in breast and ovarian cancer treatment. The success provides an...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-12-01
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| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/11/23/3877 |