A dual role of lola in Drosophila ovary development: regulating stem cell niche establishment and repressing apoptosis

Abstract In Drosophila ovary, niche is composed of somatic cells, including terminal filament cells (TFCs), cap cells (CCs) and escort cells (ECs), which provide extrinsic signals to maintain stem cell renewal or initiate cell differentiation. Niche establishment begins in larval stages when termina...

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Bibliographic Details
Main Authors: Ting Zhao, Yanhong Xiao, Bo Huang, Mao-Jiu Ran, Xin Duan, Yu-Feng Wang, Yuzhen Lu, Xiao-Qiang Yu
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05195-9