Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson’s disease brain extracts in transgenic mice

Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson’s disease brain extracts in transgenic mice

Abstract Synucleinopathies [Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA)] share filamentous α-synuclein assemblies in nerve cells and glial cells. We compared the abilities of brain extracts from MSA and PD patients to induce neuronal α-synuclein assemb...

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Bibliographic Details
Main Authors: Isabelle Lavenir, Daniela Passarella, Masami Masuda-Suzukake, Annabelle Curry, Janice L. Holton, Bernardino Ghetti, Michel Goedert
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Acta Neuropathologica Communications
Subjects:
α-Synuclein
Multiple system atrophy
Parkinson’s disease
Seeding
Silver staining
Transgenic
Online Access:http://link.springer.com/article/10.1186/s40478-019-0804-5

Internet

http://link.springer.com/article/10.1186/s40478-019-0804-5

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