Dynamic changes in kynurenine pathway metabolites in multiple sclerosis: A systematic review

Dynamic changes in kynurenine pathway metabolites in multiple sclerosis: A systematic review

BackgroundMultiple sclerosis (MS) is a debilitating neurodegenerative disorder characterized by axonal damage, demyelination, and perivascular inflammatory lesions in the white matter of the central nervous system (CNS). Kynurenine pathway (KP), which is the major route of tryptophan (TRP) metabolis...

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Bibliographic Details
Main Authors: Mobina Fathi, Kimia Vakili, Shirin Yaghoobpoor, Arian Tavasol, Kimia Jazi, Ashraf Mohamadkhani, Andis Klegeris, Alyssa McElhinney, Zahedeh Mafi, Mohammadreza Hajiesmaeili, Fatemeh Sayehmiri
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
kynurenine pathway
kynurenine
tryptophan
picolinic acid
hydroxyindoleacetic acid
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1013784/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1013784/full

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