Dynamic changes in kynurenine pathway metabolites in multiple sclerosis: A systematic review

Dynamic changes in kynurenine pathway metabolites in multiple sclerosis: A systematic review

BackgroundMultiple sclerosis (MS) is a debilitating neurodegenerative disorder characterized by axonal damage, demyelination, and perivascular inflammatory lesions in the white matter of the central nervous system (CNS). Kynurenine pathway (KP), which is the major route of tryptophan (TRP) metabolis...

Full description

Bibliographic Details
Main Authors:	Mobina Fathi, Kimia Vakili, Shirin Yaghoobpoor, Arian Tavasol, Kimia Jazi, Ashraf Mohamadkhani, Andis Klegeris, Alyssa McElhinney, Zahedeh Mafi, Mohammadreza Hajiesmaeili, Fatemeh Sayehmiri
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Series:	Frontiers in Immunology
Subjects:	multiple sclerosis kynurenine pathway kynurenine tryptophan picolinic acid hydroxyindoleacetic acid
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1013784/full

Similar Items

Dynamic changes in metabolites of the kynurenine pathway in Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease: A systematic Review and meta-analysis
by: Mobina Fathi, et al.
Published: (2022-10-01)

Kynurenine acid - metabolism and regulation of kynurenine pathway
by: Piotr Kozłowski, et al.
Published: (2017-07-01)

Kynurenine acid - metabolism and regulation of kynurenine pathway
by: Piotr Kozłowski, et al.
Published: (2017-07-01)

Different Kynurenine Pathway Dysregulation in Systemic Sclerosis in Men and Women
by: Monika Turska-Kozłowska, et al.
Published: (2024-03-01)

A Low FODMAP Diet Supplemented with L-Tryptophan Reduces the Symptoms of Functional Constipation in Elderly Patients
by: Cezary Chojnacki, et al.
Published: (2024-04-01)

Tryptophan Metabolism in Postmenopausal Women with Functional Constipation
by: Aleksandra Blonska, et al.
Published: (2023-12-01)

A systematic review and meta-analysis of the kynurenine pathway of tryptophan metabolism in rheumatic diseases
by: Arduino A. Mangoni, et al.
Published: (2023-10-01)

Role of Kynurenine Pathway in Oxidative Stress during Neurodegenerative Disorders
by: Adrian Mor, et al.
Published: (2021-06-01)

Dietary Kynurenine Pathway Metabolites—Source, Fate, and Chromatographic Determinations
by: Ilona Sadok, et al.
Published: (2023-11-01)

Kynurenine Pathway in Psoriasis—a Promising Link?
by: A. Stepaniuk, et al.
Published: (2023-06-01)

Increased Kynurenine Indicates a Fatal Course of COVID-19
by: Harald Mangge, et al.
Published: (2021-12-01)

Tryptophan recovery index as a new biomarker for fitness
by: Alexander Pichler, et al.
Published: (2022-06-01)

Targeted metabolomics suggests a probable role of the FTO gene in the kynurenine pathway in prediabetes
by: La-or Chailurkit, et al.
Published: (2022-06-01)

Kynurenine Is the Main Metabolite of Tryptophan Degradation by Tryptophan 2,3-Dioxygenase in HepaRG Tumor Cells
by: Hani Oweira, et al.
Published: (2022-08-01)

Kynurenine Monooxygenase Expression and Activity in Human Astrocytomas
by: Gustavo Ignacio Vázquez Cervantes, et al.
Published: (2021-08-01)

Folate, neopterin and kynurenine pathway in patients with statin therapy
by: Palabiyik Saziye Sezin, et al.
Published: (2016-06-01)

Identification of kynurenine and quinolinic acid as promising serum biomarkers for drug-induced interstitial lung diseases
by: Yuchen Sun, et al.
Published: (2024-01-01)

Neopterin and Kynurenine in Mesangioproliferative Glomerulonephritis
by: Martinsons Agris, et al.
Published: (1998-11-01)

Kynurenines as a Novel Target for the Treatment of Malignancies
by: Adrian Mor, et al.
Published: (2021-06-01)

Changes in Tryptophan-Kynurenine Metabolism in Patients with Depression Undergoing ECT—A Systematic Review
by: Tore Ivar Malmei Aarsland, et al.
Published: (2022-11-01)

Resistance Exercise Reduces Kynurenine Pathway Metabolites in Breast Cancer Patients Undergoing Radiotherapy
by: Philipp Zimmer, et al.
Published: (2019-09-01)

The Effect of Systemic Nitroglycerin Administration on the Kynurenine Pathway in the Rat
by: Gábor Nagy-Grócz, et al.
Published: (2017-06-01)

Kynurenine pathway metabolism and neuroinflammatory disease
by: Nady Braidy, et al.
Published: (2017-01-01)

The Kynurenine Pathway: a Proposed Mechanism Linking Diabetes and Periodontal Disease in Diabetic Patients
by: Rishabh Kapila, et al.
Published: (2011-07-01)

Serum tryptophan, kynurenine, phenylalanine, tyrosine and neopterin concentrations in 100 healthy blood donors
by: Geisler Simon, et al.
Published: (2015-03-01)

Serum profiles of tryptophan-kynurenine pathway metabolites in psoriasis
by: Mariko Seishima, et al.
Published: (2021-10-01)

Modulation of Enzyme Activity in the Kynurenine Pathway by Kynurenine Monooxygenase Inhibition
by: Robert S. Phillips, et al.
Published: (2019-02-01)

Corrigendum: The Effect of Systemic Nitroglycerin Administration on the Kynurenine Pathway in the Rat
by: Gábor Nagy-Grócz, et al.
Published: (2020-09-01)

The Kynurenine Pathway as a Potential Target for Neuropathic Pain Therapy Design: From Basic Research to Clinical Perspectives
by: Katarzyna Ciapała, et al.
Published: (2021-10-01)

Measurement of kynurenine pathway metabolites by tandem mass spectrometry
by: Sedat Abusoglu, et al.
Published: (2023-04-01)

Abnormal Activation of Tryptophan-Kynurenine Pathway in Women With Polycystic Ovary Syndrome
by: Siyu Wang, et al.
Published: (2022-06-01)

Associations of Parameters of the Tryptophan–Kynurenine Pathway with Cardiovascular Risk Factors in Hypertensive Patients
by: Verena Theiler-Schwetz, et al.
Published: (2023-01-01)

Kynurenine pathway modulation reverses the experimental autoimmune encephalomyelitis mouse disease progression
by: Gayathri Sundaram, et al.
Published: (2020-06-01)

Electrochemical Determination of Kynurenine Pathway Metabolites—Challenges and Perspectives
by: Ilona Sadok, et al.
Published: (2021-10-01)

Kynurenine Pathway Metabolites as Potential Biomarkers in Chronic Pain
by: Andrew Auyeung, et al.
Published: (2023-05-01)

An Emerging Cross-Species Marker for Organismal Health: Tryptophan-Kynurenine Pathway
by: Laiba Jamshed, et al.
Published: (2022-06-01)

Effect of Tryptophan-Derived AhR Ligands, Kynurenine, Kynurenic Acid and FICZ, on Proliferation, Cell Cycle Regulation and Cell Death of Melanoma Cells—In Vitro Studies
by: Katarzyna Walczak, et al.
Published: (2020-10-01)

Kynurenine pathway metabolites are associated with gray matter volume in subjects with schizophrenia
by: Sumiao Zhou, et al.
Published: (2022-08-01)

Twelve-week physical exercise does not have a long-lasting effect on kynurenines in plasma of depressed patients
by: Millischer V, et al.
Published: (2017-03-01)

Associations of the serum kynurenine pathway metabolites with P50 auditory gating in non-smoking patients with first-episode schizophrenia
by: Qingyan Yang, et al.
Published: (2022-10-01)