The Endocannabinoid Anandamide Attenuates Acute Respiratory Distress Syndrome by Downregulating miRNA that Target Inflammatory Pathways

The Endocannabinoid Anandamide Attenuates Acute Respiratory Distress Syndrome by Downregulating miRNA that Target Inflammatory Pathways

Acute respiratory distress syndrome (ARDS) is defined as a type of respiratory failure that is caused by a variety of insults such as pneumonia, sepsis, trauma and certain viral infections. In this study, we investigated the effect of an endocannabinoid, anandamide (AEA), on ARDS induced in the mous...

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Bibliographic Details
Main Authors: Muthanna Sultan, Hasan Alghetaa, Amirah Mohammed, Osama A. Abdulla, Paul J. Wisniewski, Narendra Singh, Prakash Nagarkatti, Mitzi Nagarkatti
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
acute respiratory distress syndrome (ARDS)
anandamide (AEA)
staphylococcus enterotoxin B (SEB)
micro-RNA (miRNA/miR)
myeloid derived suppressor cells (MDSC)
T regulatory cells (T regs)
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.644281/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.644281/full

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