Genome-wide gene expression profiling of nucleus accumbens neurons projecting to ventral pallidum using both microarray and transcriptome sequencing

Genome-wide gene expression profiling of nucleus accumbens neurons projecting to ventral pallidum using both microarray and transcriptome sequencing

The cellular heterogeneity of brain poses a particularly thorny issue in genome-wide gene expression studies. Because laser capture microdissection (LCM) enables the precise extraction of a small area of tissue, we combined LCM with neuronal track-tracing to collect nucleus accumbens shell neurons...

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Bibliographic Details
Main Authors: Hao eChen, Zhimin eLiu, Suzhen eGong, Xingjun eWu, William L Taylor, Robert W Williams, Shannon G Matta, Burt M Sharp
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-08-01
Series:Frontiers in Neuroscience
Subjects:
Nucleus Accumbens
GABA
Microarray
GABAergic
Laser capture microdissectio
RNA sequencing
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00098/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00098/full

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