Defining a Correlative Transcriptional Signature Associated with Bulk Histone H3 Acetylation Levels in Adult Glioblastomas

Defining a Correlative Transcriptional Signature Associated with Bulk Histone H3 Acetylation Levels in Adult Glioblastomas

Glioblastoma (GB) is the most prevalent primary brain cancer and the most aggressive form of glioma because of its poor prognosis and high recurrence. To confirm the importance of epigenetics in glioma, we explored The Cancer Gene Atlas (TCGA) database and we found that several histone/DNA modificat...

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Bibliographic Details
Main Authors: Irati Hervás-Corpión, Jorge Navarro-Calvo, Paula Martín-Climent, Marianela Iriarte-Gahete, Noelia Geribaldi-Doldán, Carmen Castro, Luis M. Valor
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
glioma
epigenetics
histone
acetylation
RNA-seq
HDACi
Online Access:https://www.mdpi.com/2073-4409/12/3/374

Internet

https://www.mdpi.com/2073-4409/12/3/374

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