Analysis of the Physicochemical Properties, Replication and Pathophysiology of a Massively Glycosylated Hepatitis B Virus HBsAg Escape Mutant

Mutations in HBsAg, the surface antigen of the hepatitis B virus (HBV), might affect the serum HBV DNA level of HBV-infected patients, since the reverse transcriptase (RT) domain of HBV polymerase overlaps with the HBsAg-coding region. We previously identified a diagnostic escape mutant (W3S) HBV th...

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Bibliographic Details
Main Authors: Md. Golzar Hossain, Yadarat Suwanmanee, Kaili Du, Keiji Ueda
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/11/2328