Case report: Durable response to ruxolitinib in a child with TREX1-related disorder

Case report: Durable response to ruxolitinib in a child with TREX1-related disorder

BackgroundJAK inhibitors are useful in treating interferonopathies, presumably because they downregulate the JAK/STAT signaling. There are limited studies about the safety and effectiveness of using JAK inhibitors in children with TREX1-related disorders.Case presentationWe report an 8-year-old fema...

Full description

Bibliographic Details
Main Authors: Yasir Bin Khathlan, Sajdi Almutairi, Fahad B. Albadr, Abdullah A. Alangari, Abdulrahman Alsultan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Pediatrics
Subjects:
TREX1 gene
JAK—STAT signaling pathway
ruxolinitib
child
pancytopenia
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1178919/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2023.1178919/full

Similar Items