A blueprint for a multi-disease, multi-domain Bayesian adaptive platform trial incorporating adult and paediatric subgroups: the Staphylococcus aureus Network Adaptive Platform trial

A blueprint for a multi-disease, multi-domain Bayesian adaptive platform trial incorporating adult and paediatric subgroups: the Staphylococcus aureus Network Adaptive Platform trial

Abstract The Staphylococcus aureus Network Adaptive Platform (SNAP) trial is a multifactorial Bayesian adaptive platform trial that aims to improve the way that S. aureus bloodstream infection, a globally common and severe infectious disease, is treated. In a world first, the SNAP trial will simulta...

Full description

Bibliographic Details
Main Authors: Robert K. Mahar, Anna McGlothlin, Michael Dymock, Todd C. Lee, Roger J. Lewis, Thomas Lumley, Jocelyn Mora, David J. Price, Benjamin R. Saville, Tom Snelling, Rebecca Turner, Steven A. Webb, Joshua S. Davis, Steven Y. C. Tong, Julie A. Marsh, on behalf of the SNAP Global Trial Steering Committee
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Trials
Subjects:
Bayesian
Platform
Staphylococcus aureus
Trial
Randomised
Adaptive
Online Access:https://doi.org/10.1186/s13063-023-07718-x

Internet

https://doi.org/10.1186/s13063-023-07718-x

Similar Items