Common mutations identified in the MLH1 gene in familial Lynch syndrome
Lynch syndrome (Hereditary Non Polyposis Colorectal Cancer, HNPCC) is one of the most common hereditary familial colorectal cancers (CRC) with an autosomal dominant pattern of inheritance. It accounts for 2-5% of the total CRCs reported worldwide. Although a lower incidence for CRCs have been observ...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Science Planet Inc.
2017-12-01
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Series: | Canadian Journal of Biotechnology |
Online Access: | https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue-Supplement/cjb.2017-a238.pdf |