Common mutations identified in the MLH1 gene in familial Lynch syndrome

Lynch syndrome (Hereditary Non Polyposis Colorectal Cancer, HNPCC) is one of the most common hereditary familial colorectal cancers (CRC) with an autosomal dominant pattern of inheritance. It accounts for 2-5% of the total CRCs reported worldwide. Although a lower incidence for CRCs have been observ...

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Bibliographic Details
Main Authors: Jisha Elias, Coral Karunakaran, Snigdha Majumder, Malini Manoharan, Rakshit Shah, Yogesh Mistry, Rajesh Ramanuj, Niraj Bhatt, Arati Khanna- Gupta
Format: Article
Language:English
Published: Science Planet Inc. 2017-12-01
Series:Canadian Journal of Biotechnology
Online Access:https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue-Supplement/cjb.2017-a238.pdf