Induction of TLR4/TLR2 Interaction and Heterodimer Formation by Low Endotoxic Atypical LPS

Induction of TLR4/TLR2 Interaction and Heterodimer Formation by Low Endotoxic Atypical LPS

The Toll-like receptor 4 (TLR4)/myeloid differentiation protein-2 (MD-2) complex is considered the major receptor of the innate immune system to recognize lipopolysaccharides (LPSs). However, some atypical LPSs with different lipid A and core saccharide moiety structures and compositions than the we...

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Bibliographic Details
Main Authors: Sara Francisco, Jean-Marc Billod, Javier Merino, Carmen Punzón, Alicia Gallego, Alicia Arranz, Sonsoles Martin-Santamaria, Manuel Fresno
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
Toll-like receptors
macrophages
innate immunity
atypical-LPS
cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.748303/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.748303/full

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