Therapeutic Potential and Challenges of Pioglitazone in Cancer Treatment

Pioglitazone (ACTOS) is a thiazolidinedione for peroxisome proliferator-activated receptor γ (PPAR-γ) that has been well established for the second or third line treatment of type 2 diabetes mellitus. Beyond the effects on glucose metabolism, pioglitazone displays positive effects on lipid metabolis...

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Bibliographic Details
Main Authors: Maria Vasileiou, Sotirios Charalampos Diamantoudis, Christina Tsianava, Nam P. Nguyen
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/15/4/1925