A recombinant Modified Vaccinia virus Ankara expressing prME of tick-borne encephalitis virus affords mice full protection against TBEV infection

A recombinant Modified Vaccinia virus Ankara expressing prME of tick-borne encephalitis virus affords mice full protection against TBEV infection

IntroductionTick-borne encephalitis virus (TBEV) is an important human pathogen that can cause a serious disease involving the central nervous system (tick-borne encephalitis, TBE). Although approved inactivated vaccines are available, the number of TBE cases is rising, and breakthrough infections i...

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Bibliographic Details
Main Authors: Mareike Kubinski, Jana Beicht, Isabel Zdora, Jeannine Biermann, Christina Puff, Thomas Gerlach, Alina Tscherne, Wolfgang Baumgärtner, Albert D. M. E. Osterhaus, Gerd Sutter, Chittappen Kandiyil Prajeeth, Guus F. Rimmelzwaan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
TBEV
MVA
FSME-IMMUN®
protection
vaccination
virus-neutralizing antibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1182963/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1182963/full

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