A recombinant Modified Vaccinia virus Ankara expressing prME of tick-borne encephalitis virus affords mice full protection against TBEV infection

A recombinant Modified Vaccinia virus Ankara expressing prME of tick-borne encephalitis virus affords mice full protection against TBEV infection

IntroductionTick-borne encephalitis virus (TBEV) is an important human pathogen that can cause a serious disease involving the central nervous system (tick-borne encephalitis, TBE). Although approved inactivated vaccines are available, the number of TBE cases is rising, and breakthrough infections i...

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Bibliographic Details
Main Authors:	Mareike Kubinski, Jana Beicht, Isabel Zdora, Jeannine Biermann, Christina Puff, Thomas Gerlach, Alina Tscherne, Wolfgang Baumgärtner, Albert D. M. E. Osterhaus, Gerd Sutter, Chittappen Kandiyil Prajeeth, Guus F. Rimmelzwaan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-04-01
Series:	Frontiers in Immunology
Subjects:	TBEV MVA FSME-IMMUN® protection vaccination virus-neutralizing antibodies
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1182963/full

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