Geranylgeranylacetone Ameliorates Skin Inflammation by Regulating and Inducing Thioredoxin via the Thioredoxin Redox System

Geranylgeranylacetone Ameliorates Skin Inflammation by Regulating and Inducing Thioredoxin via the Thioredoxin Redox System

Geranylgeranylacetone (GGA) exerts cytoprotective activity against various toxic stressors via the thioredoxin (TRX) redox system; however, its effect on skin inflammation and molecular mechanism on inducing the TRX of GGA is still unknown. We investigated the effects of GGA in a murine irritant con...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Tiancheng Jin, Yitong You, Wenjie Fan, Junyang Wang, Yuhao Chen, Shujing Li, Siyuan Hong, Yaxuan Wang, Ruijie Cao, Junji Yodoi, Hai Tian
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: MDPI AG 2023-08-01
Loạt:Antioxidants
Những chủ đề:
geranylgeranylacetone
irritant contact dermatitis
thioredoxin redox system
PI3K/Akt/Nrf2 signaling pathway
anti-inflammatory effect and mechanism
Truy cập trực tuyến:https://www.mdpi.com/2076-3921/12/9/1701

Internet

https://www.mdpi.com/2076-3921/12/9/1701

Những quyển sách tương tự