Genetic association of beta-lactams-induced hypersensitivity reactions: A systematic review of genome-wide evidence and meta-analysis of candidate genes

Genetic association of beta-lactams-induced hypersensitivity reactions: A systematic review of genome-wide evidence and meta-analysis of candidate genes

Importance: Beta-lactams (BLs) are the most prescribed antibiotics, being the most frequent cause of drug allergy. However, the association between BL allergy and genetic variations is still unclear. Objective: This systematic review and meta-analysis aimed to summarize the genetic effects of BL-ind...

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Bibliographic Details
Main Authors: Lalita Lumkul, M.Sc, Pakpoom Wongyikul, M.D., Prapasri Kulalert, M.D., Ph.D, Mongkhon Sompornrattanaphan, M.D., Mongkol Lao-Araya, M.D., Mati Chuamanochan, M.D., Surapon Nochaiwong, Pharm.D., Phichayut Phinyo, M.D., Ph.D
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:World Allergy Organization Journal
Subjects:
Beta lactams hypersensitivity
Genetic polymorphism
Genome-wide association study
Systematic review
Meta-analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455123000765

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http://www.sciencedirect.com/science/article/pii/S1939455123000765

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