Induction of neutralizing antibodies in mice immunized with scorpion toxins detoxified by liposomal entrapment

The possibility of producing neutralizing antibodies against the lethal effects of scorpion toxins was evaluated in the mouse model by immunization with an immunogen devoid of toxicity. A toxic fraction (5 mg) from the venom of the scorpion Tityus serrulatus was entrapped in sphingomyelin-cholestero...

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Bibliographic Details
Main Authors: S.G. Fonseca, A.M.M. Ferreira, C.R. Diniz, C. Chávez-Olórtegui
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1997-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000700010