Senescent Colon and Breast Cancer Cells Induced by Doxorubicin Exhibit Enhanced Sensitivity to Curcumin, Caffeine, and Thymoquinone

Senescent Colon and Breast Cancer Cells Induced by Doxorubicin Exhibit Enhanced Sensitivity to Curcumin, Caffeine, and Thymoquinone

Cellular senescence is a process of physiological growth arrest that can be induced by intrinsic or extrinsic stress signals. Some cancer therapies are associated with senescence of cancer cells with a typical cell cycle arrest. Doxorubicin (Dox) induces senescence by a p53-dependent pathway and tel...

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Bibliographic Details
Main Authors: Ali H. El-Far, Noureldien H. E. Darwish, Shaker A. Mousa PhD, MBA, FACC, FACB
Format: Article
Language:English
Published: SAGE Publishing 2020-01-01
Series:Integrative Cancer Therapies
Online Access:https://doi.org/10.1177/1534735419901160

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https://doi.org/10.1177/1534735419901160

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