Dense neural networks for predicting chromatin conformation

Abstract Background DNA inside eukaryotic cells wraps around histones to form the 11nm chromatin fiber that can further fold into higher-order DNA loops, which may depend on the binding of architectural factors. Predicting how the DNA will fold given a distribution of bound factors, here viewed as a...

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Bibliographic Details
Main Authors: Pau Farré, Alexandre Heurteau, Olivier Cuvier, Eldon Emberly
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2286-z