NG2 MOLECULE EXPRESSION IN ACUTE LYMPHOBLASTIC LEUKEMIA B CELLS: A FLOW-CYTOMETRIC MARKER FOR THE RAPID IDENTIFICATION OF KMT2A GENE REARRANGEMENTS

NG2 MOLECULE EXPRESSION IN ACUTE LYMPHOBLASTIC LEUKEMIA B CELLS: A FLOW-CYTOMETRIC MARKER FOR THE RAPID IDENTIFICATION OF KMT2A GENE REARRANGEMENTS

Background: B-lineage acute lymphoblastic leukemias (B-ALL) harboring rearrangements of the histone lysine [K]-Methyltransferase 2A (KMT2A) gene on chromosome 11q23 (KMT2A-r), represent a category with dismal prognosis. The prompt identification of these cases represents an urgent clinical need....

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Bibliographic Details
Main Authors: Maria Laura Bisegna, Nadia Peragine, Loredana Elia, Mabel Matarazzo, Maria Laura Milani, Stefania Intoppa, Mariangela Di Trani, Francesco Malfona, Maurizio Martelli, Maria Stefania De Propris
Format: Article
Language:English
Published: PAGEPress Publications 2024-02-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
NG2
flow-cytometry
acute lymphoblastic leukemia
KMT2A gene rearrangements
Online Access:https://www.mjhid.org/mjhid/article/view/5523

Internet

https://www.mjhid.org/mjhid/article/view/5523

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