Characterization and quantitation of busulfan DNA adducts in the blood of patients receiving busulfan therapy

DNA alkylating drugs have been used as cancer chemotherapy with variable outcomes. The establishment of predictive biomarkers to identify patients who will effectively respond to treatment would allow for the development of personalized therapies. As the degree of interaction of alkylating drug with...

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Bibliographic Details
Main Authors: Valeria Guidolin, Yupeng Li, Foster C. Jacobs, Margaret L. MacMillan, Peter W. Villalta, Stephen S. Hecht, Silvia Balbo
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Molecular Therapy: Oncolytics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770523000074