Folate Transport and One-Carbon Metabolism in Targeted Therapies of Epithelial Ovarian Cancer

Folate Transport and One-Carbon Metabolism in Targeted Therapies of Epithelial Ovarian Cancer

New therapies are urgently needed for epithelial ovarian cancer (EOC), the most lethal gynecologic malignancy. To identify new approaches for targeting EOC, metabolic vulnerabilities must be discovered and strategies for the selective delivery of therapeutic agents must be established. Folate recept...

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Bibliographic Details
Main Authors: Adrianne Wallace-Povirk, Zhanjun Hou, Md. Junayed Nayeen, Aleem Gangjee, Larry H. Matherly
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
epithelial ovarian cancer
folate
folate receptor
folate transport
one-carbon metabolism
proton-coupled folate transporter
Online Access:https://www.mdpi.com/2072-6694/14/1/191

Internet

https://www.mdpi.com/2072-6694/14/1/191

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