High-throughput drug screening allowed identification of entry inhibitors specifically targeting different routes of SARS-CoV-2 Delta and Omicron/BA.1

High-throughput drug screening allowed identification of entry inhibitors specifically targeting different routes of SARS-CoV-2 Delta and Omicron/BA.1

The Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2) has continuously evolved, resulting in the emergence of several variants of concern (VOCs). To study mechanisms of viral entry and potentially identify specific inhibitors, we pseudotyped lentiviral vectors with different SARS-CoV...

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Bibliographic Details
Main Authors: Maria Kuzikov, Jannis Woens, Andrea Zaliani, Julia Hambach, Thomas Eden, Boris Fehse, Bernhard Ellinger, Kristoffer Riecken
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
SARS-CoV-2
Pseudovirus
Lentiviral vector
Variant of concern
D614G
Delta
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222004930

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http://www.sciencedirect.com/science/article/pii/S0753332222004930

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