Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival.

Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival.

<h4>Background</h4>Heparan sulfate proteoglycans (HSPGs) use highly sulfated polysaccharide side-chains to interact with several key growth factors and morphogens, thereby regulating their accessibility and biological activity. Various sulfotransferases and sulfatases with differing spec...

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Bibliographic Details
Main Authors: Charles R Holst, Hani Bou-Reslan, Bryan B Gore, Karen Wong, Deanna Grant, Sreedevi Chalasani, Richard A Carano, Gretchen D Frantz, Marc Tessier-Lavigne, Brad Bolon, Dorothy M French, Avi Ashkenazi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0000575

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https://doi.org/10.1371/journal.pone.0000575

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